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KMID : 1038820150180020144
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Pediatric Gastroenterology, Hepatology & Nutrition
2015 Volume.18 No. 2 p.144 ~ p.148
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Atypical β-Catenin Activated Child Hepatocellular Tumor
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Aynur Turan
Havva Akmaz Unlu
Esra Karakus
Arzu Yazal Erdem
Zeynep Ilerisoy Yakut
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Abstract
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Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The β-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular ad-enomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of β-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1α-inactivated hepatocellular adenomas subtype, has not been pre-viously reported in any β-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.
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KEYWORD
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Adenoma, Liver, Hepatocellular carcinoma, Magnetic resonance imaging, Beta-catenin
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